The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein.
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
ITGAL
Reactivity: Human
FACS, IP
Host: Mouse
Monoclonal
MEM-25
Biotin
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Storage
4 °C
Storage Comment
The product should be stored undiluted at 4°C. Do not freeze.
Target
ITGAL
(Integrin alpha-L (ITGAL))
Alternative Name
CD11a
Background
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2).